Overview
Influence of a Bolus Administration of Ephedrine and Phenylephrine on the Spinal Oxygen Saturation, Measured With NIRS.
Status:
Completed
Completed
Trial end date:
2018-12-04
2018-12-04
Target enrollment:
0
0
Participant gender:
All
All
Summary
To evaluate the influence of vasoactive medication on the spinal vasculature, we have chosen patients scheduled for arterial dilation of the lower limb as our study population. In these patients the spinal cord perfusion is not compromised. However, most patients will suffer from hypotension during surgery, due to the non-invasive type of surgery and the vasodilating effects of the anesthetics. Therefore, bolus administration of vasoactive medication (ephedrine, phenylephrine) is routinely required in order to increase the blood pressure. The aim of the study is to observe the influence of a bolus administration of ephedrine and phenylephrine on the spinal vasculature, measured by NIRS.Phase:
Phase 4Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
University Hospital, GhentTreatments:
Ephedrine
Oxymetazoline
Phenylephrine
Pseudoephedrine
Criteria
Inclusion Criteria:- Patients > 18y
- scheduled for dilation of arterial blood vessels of the lower limb
Exclusion Criteria:
- Age < 18y
- BMI > 30
- severe valvular disease
- previous aortic surgery
- paraplegia/ paraparesis
- renal replacement therapy