Influence of the Noradrenergic System on the Formation of Intrusive Memories

• Status: Completed
• Trial end date: 2014-10-01
• Target enrollment: 0
• Participant gender: Female

Summary

Intrusive memories of traumatic events are core features of posttraumatic stress disorder (PTSD) but little is known about the neurobiological formation of intrusions. The aim of this study was to determine whether the activity of the noradrenergic system during an intrusion-inducing stressor influences subsequent intrusive memories.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Charite University, Berlin, Germany
• Treatments: Clonidine; Yohimbine

Criteria

Inclusion Criteria:

• healthy participants

• German on a native level

Exclusion Criteria:

• former or present DSM IV Axis I disorders

• physical illnesses

• any medication intake (except oral contraceptive)

• history of sexual abuse or rape

• pregnancy or lactation period