Overview

Influences of Angiotensin-neprilysin Inhibition on Sympathetic Activity in Heart Failure

Status:
Withdrawn
Trial end date:
2018-09-06
Target enrollment:
Participant gender:
Summary
The autonomic nervous system plays an important role in controlling the circulation. Increased sympathetic activity has detrimental effects in patients with heart failure. The purpose of this study is to test the hypothesis that combined angiotensin receptor + neprilysin inhibition results in lower sympathetic activity than angiotensin receptor inhibition alone.
Phase:
Phase 2
Details
Lead Sponsor:
Hannover Medical School
Collaborator:
DLR German Aerospace Center
Treatments:
Angiotensin Receptor Antagonists
LCZ 696
Valsartan