Influencing Wound Healing Through the Application of Hyaluronic Acid With Perfluorodecalin and Physalis Angulata Extract After Split Skin Removal From the Thigh - A Study in "Split Wound Design"

• Status: Withdrawn
• Trial end date: 2020-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The study will use a split wound design to investigate whether secondary wound healing can be accelerated and improved by the application of hyaluronic acid combined with perfluorodecalin and Physalis angulata extract.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: RWTH Aachen University
• Treatments: Hyaluronic Acid

Criteria

Inclusion Criteria:

• Age between 18-90 years

• Split skin removal at the thigh must be planned for the patients

• Adult patients who are mentally and physically able to understand the importance and scope of the study and to follow up the study staff

• Written informed consent before participating in the study

Exclusion Criteria:

• Patients suffering from a systemic disease (e.g. diabetes mellitus, anticoagulant therapy,...)

• Patients taking immunosuppressive drugs that may affect wound healing

• Patients suffering from skin diseases

• Pregnant and/or lactating women. Women of childbearing age should protect themselves from potential pregnancy by adequate contraception while participating in studies.

• Participation in a study may, at the investigator's discretion, present an unacceptable risk due to pre- or concomitant disease or the patient's general underlying condition.

• Underage, or older than 90 years

• Life span is less than six months

• There is a current or past medically relevant disease or treatment that could influence the evaluation of the study

• The patient has received a study medication within the last 30 days as part of another study

• Simultaneous participation in another clinical intervention study

• Expected lack of compliance

• Alcohol or drug abuse

• The patient is accommodated in an institution by official or court order

• Patients in a dependent relationship or employment relationship with the sponsor, investigator, or alternate investigator