Infusion of Panobinostat (MTX110) Into the Fourth Ventricle in Children and Adults With Recurrent Medulloblastoma
Status:
Recruiting
Trial end date:
2022-12-30
Target enrollment:
Participant gender:
Summary
The purpose of this study is to establish the safety of infusions of panobinostat (MTX110)
into the fourth ventricle of the brain or tumor resection cavity in patients with recurrent
medulloblastoma and to assess the antitumor activity of simultaneous infusions of
panobinostat (MTX110) into the fourth ventricle of the brain or resection cavity in patients
with recurrent medulloblastoma based upon MRI scans and lumbar cerebrospinal fluid (CSF)
cytology.
Phase:
Early Phase 1
Details
Lead Sponsor:
The University of Texas Health Science Center, Houston