Inhaled Nitric Oxide (iNO) as an Adjunct to Neonatal Resuscitation

• Status: Completed
• Trial end date: 2017-05-01
• Target enrollment: 0
• Participant gender: All

Summary

This study hopes to determine whether nitric oxide along with oxygen during the first 20 minutes of life in infants needing help with breathing will reduce the percentage and total exposure to oxygen during that time frame. Although the use of oxygen in management of breathing is an important part of supporting baby immediately after delivery, there is more evidence that too much exposure to oxygen may lead to potential problems for your baby later. Oxygen exposure can be harmful to premature babies developing lungs.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Oklahoma
• Collaborator: Mallinckrodt
• Treatments: Nitric Oxide

Criteria

Inclusion Criteria:

• Infants that are 25 0/7 - 31 6/7 weeks gestation

• Infants who require Continuous Positive Airway Pressure (CPAP) or Positive Pressure Ventilation ( PPV) during delivery room resuscitation.

Exclusion Criteria:

• Refusal of consent

• Known complex congenital anomalies of the heart or lungs

• Known major genetic defects

• Hydrops fetalis