Inhaled Nitric Oxide in Pulmonary Embolism

• Status: Completed
• Trial end date: 2009-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine if inhaled nitric oxide, a potent and selective pulmonary vasodilator, is beneficial in patients with acute pulmonary embolism causing increased right ventricular afterload.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical University of Vienna
• Treatments: Nitric Oxide

Criteria

Inclusion Criteria:

• Patients with acute pulmonary embolism within 24 hours after onset of symptoms.

• Patients with hypoxaemia not present before pulmonary embolism and acute right ventricular dysfunction.

Exclusion Criteria:

• Age < 18 years.

• Chronic lung disease, left heart failure, suspected or documented intracranial bleeding.

• Pregnancy, Methaemoglobinaemia.

• Patients who previously needed thrombolysis or surgical embolectomy.

• Negative D-Dimer test.