Inhaled Nitrite in Subjects With Pulmonary Hypertension
Status:
Completed
Trial end date:
2017-10-01
Target enrollment:
Participant gender:
Summary
This is a single-center, open label phase II study to evaluate the effect of inhaled nitrite
delivered in a dose escalation manner on the change in pulmonary vascular resistance (PVR) in
subjects with pulmonary hypertension undergoing right heart catheterization.
A total of 50 subjects with a confirmed diagnosis of pulmonary hypertension and meet all
inclusion/exclusion criteria will be enrolled in the study which will entail a single right
heart catheterization and nebulized nitrite dose of 45mg with one subsequent dosage of 90 mg.