Inhaler Lung Deposition in Chronic Obstructive Pulmonary Disease (COPD)
Status:
Unknown status
Trial end date:
2016-02-01
Target enrollment:
Participant gender:
Summary
Patients with chronic obstructive pulmonary disease (COPD) experience breathing difficulties
because the airways deep in their lungs become narrowed. COPD patients use inhaler drugs to
provide relief from breathlessness. However, current inhalers are inefficient as they deliver
a 'coarse-mist' of drug-droplets that do not reach the deep airways.
In our study, we will use an inhaler of 'fine-mist' drug-droplets, tagged with a radioactive
tracer to track them. We will take images of the lungs to see if the fine-mist droplets reach
the deep airways, and assess if this improves the breathing capacity in our patients. Our
research may allow the development of new, more efficient inhalers to improve treatment for
patients with COPD.
Phase:
Phase 4
Details
Lead Sponsor:
Imperial College London
Collaborator:
National Institute for Health Research, United Kingdom