Inhibition of Aldosterone in Patients With Chronic Renal Disease

• Status: Completed
• Trial end date: 2009-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to examine whether the inhibition of aldosterone will result in lower excretion of protein via urine. The hypothesis is that if loss of protein is lowered, progression of renal disease with be slower than otherwise expected.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lene Boesby
• Collaborator: Rigshospitalet, Denmark
• Treatments: Eplerenone

Criteria

Inclusion Criteria:

• Proteinuria > 500 mg/24 hours

• Hypertension or anti-hypertensive treatment

Exclusion Criteria:

• Diabetic nephropathy

• GFR< 20 ml/min

• P-potassium between 3,5 mmol/l and 5,0 mmol/l