Injection Therapy in Patients With Lateral Epicondylitis

• Status: Completed
• Trial end date: 2018-09-25
• Target enrollment: 0
• Participant gender: All

Summary

Lateral epicondylitis is a painful enthesopathy of the common extensor tendon at the lateral part of the elbow, with a prevalence of 1-3 % in the general population. In the treatment of lateral epicondylitis, the role of biological-based therapies has begun to investigate regeneration and optimize tendon healing. Prolotherapy (PrT) and hyaluronic acid (HA) injections are biological based treatments. Previous studies have shown benefit of PrT in the treatment of tendinopathies. Preliminary findings demonstrated that HA could be clinically effective in the treatment of enthesopathies. Considering the paucity of HA studies (which also lack a control group) and the proposed mechanism of action of both PrT and HA is through cell proliferation and the healing process of tendons, this study was conducted to compare the effect of PrT and HA in chronic lateral epicondylitis .

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hacettepe University
• Treatments: Hyaluronic Acid

Criteria

Inclusion Criteria:

1. aged 20-60 years,

2. had a clinical diagnosis of lateral epicondylitis, defined as pain over the lateral humeral epicondyle of at least 6 months' duration,

3. provoked by palpation and resisted wrist/middle finger extension or gripping,

4. participants needed to score at least 30/100 on Visual analogue scale (VAS),

5. be able to understand enough Turkish to complete the outcome questionnaire.

Exclusion Criteria:

1. Any treatment for their elbow pain by a health care practitioner within the preceding 6 months,

2. Concomitant neck or other arm pain causing disability or requiring treatment within the last 6 months,

3. Clinical evidence of other primary sources of lateral elbow pain,

4. Upper limb fractures within the preceding 10 years,

5. Prior elbow surgery

6. Elbow steroid injection in the past 3 months

7. Systemic inflammatory disorder or malignancy,

8. Pregnancy or breastfeeding