Injection Therapy in Patients With Lateral Epicondylitis
Status:
Completed
Trial end date:
2018-09-25
Target enrollment:
Participant gender:
Summary
Lateral epicondylitis is a painful enthesopathy of the common extensor tendon at the lateral
part of the elbow, with a prevalence of 1-3 % in the general population. In the treatment of
lateral epicondylitis, the role of biological-based therapies has begun to investigate
regeneration and optimize tendon healing. Prolotherapy (PrT) and hyaluronic acid (HA)
injections are biological based treatments. Previous studies have shown benefit of PrT in the
treatment of tendinopathies. Preliminary findings demonstrated that HA could be clinically
effective in the treatment of enthesopathies. Considering the paucity of HA studies (which
also lack a control group) and the proposed mechanism of action of both PrT and HA is through
cell proliferation and the healing process of tendons, this study was conducted to compare
the effect of PrT and HA in chronic lateral epicondylitis .