Inorganic Nitrate: Sex Differences in Muscle Contractile Function and Efficiency
Status:
Recruiting
Trial end date:
2021-12-30
Target enrollment:
Participant gender:
Summary
Dietary inorganic nitrate, in the form of beet root juice, is a nutritional intervention,
considered to be an exercise enhancer due to its capacity to increase Nitric Oxide (NO)
bioavailability. Increasing NO bioavailability has been associated with improved
mitochondrial respiration, muscle tissue perfusion and contractile function which may lead to
improved exercise capacity. However, the majority of the literature is on male subjects. This
limits the applicability of this supplement in females. Therefore, our project aims to
determine sex-differences and the specific sex-response across the menstrual cycle of dietary
nitrate supplementation on exercise efficiency, strength and fatigue resistance.