Insulin Bolus Required for High Fat Foods in Type 1 Diabetes
Status:
Completed
Trial end date:
2015-04-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate an insulin bolus for use to cover higher fat meals.
Subjects will have several admissions during which the investigators will apply an iterative
dose escalation protocol to derive an optimized insulin bolus dose (carbohydrate-to-insulin
ratio for fat to minimize postprandial hyperglycemia following higher fat meals. The
investigators hypothesize that the incremental insulin dose required to cover dietary fat in
patients with type 1 diabetes will be related to total daily insulin dose (U/kg).
Phase:
N/A
Details
Lead Sponsor:
Joslin Diabetes Center
Collaborators:
Boston Children's Hospital Boston Children’s Hospital