Increasing evidence from clinical studies in Intensive Care Unit (ICU) settings indicates
that insulin infusion can improve outcome measures for patients with hyperglycemia (high
blood sugar) independent of a previous diagnosis of diabetes mellitus. This improvement in
health could also apply to patients that have high blood sugars in various other non-critical
care areas of the hospital as well. However, the data that shows improvement in health
outcomes has been collected from wards that have a lower patient to provider and patient to
nurse ratio, resulting in the ability for a much tighter control of the insulin infusion. We
hypothesize that tight blood glucose control will provide the same benefits for patients in
non-intensive care units settings but that these protocols may lead to a higher incidence of
hypoglycemia (low blood sugar) and potentially to adverse outcomes in patients.
This study aims to determine the clinical outcome of patients treated with insulin infusion
as well as the rate of hypoglycemic episodes in non-intensive areas. We will conduct a chart
review of patients treated with insulin infusions in non-critical wards at Emory University
Hospital during the period of 7/1/04 to 6/30/05. Medical records of all patients treated with
intravenous insulin infusion protocols will be analyzed. Data on demographics, laboratory
values, mortality rate, rate of hypoglycemic events, length of stay, as well as disposition
at discharge will be analyzed.