Insulin Sensitivity and Metabolism Before and After Treatment in Patients With Hypothyroidism

• Status: Terminated
• Trial end date: 2011-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to further characterize the treatment related changes in insulin sensitivity, substrate metabolism and intra hepatic- and intramyocellular lipid content in patients with hypothyroidism

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Aarhus
• Collaborator: MR Research Center, Skejby Sygehus, Brendstrupgaardsvej 100, 8200 Aarhus N
• Treatments: Insulin; Insulin, Globin Zinc

Criteria

Inclusion Criteria:

• written informed consent

• must be of legal age and competent

• Age > 18 years

• presently diagnosed with hypothyroidism

Exclusion Criteria:

• alcohol consumption >21 units per week

• Malignant disease

• pregnancy

• magnetic implants or material in the body

• BMI > 30

• Heart disease (NYHA >2)

• Uncontrolled hypertension

• Manifest diabetes mellitus

• Changes in medication, with any influence on glucose metabolism, 2 months prior to and until the end of the trial.