Integrated Management Enhances Functional Gains in Children With Cerebral Palsy Treated by BoNT-A
Status:
Completed
Trial end date:
2020-01-30
Target enrollment:
Participant gender:
Summary
Evidence from literature support the use of Botulinum toxin A (BoNT-A) for upper limb
spasticity management in children with cerebral palsy (CP). Constraint Induced Movement
Therapy (CIMT) and Bilateral Intensive Training (BIT) are indicated as effective and
complimentary treatments to improve motor function in these children. In a recent trial
combined noninvasiv brain stimulation and CIMT enhanced therapy induced functional gains.
In this clinical trial the aim was to evaluate the effects of transcranial direct current
stimulation (t-DCS) plus intensive hybrid training model of modified CIMT and BIT when
integrated with BoNT-A treatment in children with unilateral CP.
Phase:
Phase 3
Details
Lead Sponsor:
Kocaeli University
Treatments:
abobotulinumtoxinA Botulinum Toxins Botulinum Toxins, Type A onabotulinumtoxinA