Integrated Treatment Protocol for Acute Malnutrition: A Non Inferiority Trial in Burkina Faso

• Status: Completed
• Trial end date: 2018-04-01
• Target enrollment: 0
• Participant gender: All

Summary

MUAC only is a pilot trial external control carried out between January 2017 and December 2017 in the Yako district (northern region), Burkina Faso.

The objective of this study is to evaluate an integrated protocol for acute malnourished children without medical complication. The hypotheses of the integrated protocol include :

1. A global treatment of acute malnutrition (moderate and severe) with a single treatment (RUTF) would improve the functioning of the program through early identification of acutely malnourished children, while achieving a better coverage and using a single supply chain.

2. A gradual reduction of RUTF dosage according to a child's MUAC status could significantly increase the number of children on treatment without increasing overall RUTF quantity while maintaining similar recovery rates.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Alliance for International Medical Action
• Collaborators: Association Keoogo; Institut de Recherche en Sciences de la Sante, Burkina Faso; Institut National de la Santé Et de la Recherche Médicale, France; SOS médecins Burkina Faso

Criteria

Inclusion Criteria:

• Being between 6 and 59 months old

• New admission

• Acute malnutrition defined as follows:

• MUAC<125mm

• MUAC> 125mm AND WHZ (Z-score) <-3 (WHO standard)

• Edema

• Resident in the study area (Yako district)

• Signed informed consent of the mother or the child's guardian

Exclusion Criteria:

• Children allergic to milk, peanuts and / or RUTF