Integrated Treatment for Cocaine and Mood Disorders - 1

• Status: Completed
• Trial end date: 2005-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to test whether cognitive behavioral therapy and bupropion hydrochloride will help cocaine users, who are depressed, reduce or end their cocaine use and improve their mood.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: National Institute on Drug Abuse (NIDA)
• Treatments: Bupropion; Cocaine

Criteria

Inclusion Criteria:

• Generally physically healthy

• Aged 18-55

• Meets cocaine dependence by DSM-IV criteria

• Meets major depressive disorder or substance-induced depression disorder by DSM-IV criteria.

• Willing and able to participate in the 12 week treatment study and one year follow up.

Exclusion Criteria:

• Pregnant or breastfeeding.

• Taking medications that interact with the study medication (MAO inhibitors, anticonvulsants, haloperidol, phenothiazines,selegiline, anesthetics

• Have other psychiatric diagnoses requiring therapy or medication.

• Physically dependent on opiates or alcohol.

• Currently being treated with bupropion hydrochloride (e.g. Zyban).