Intensity-Modulated Radiation Therapy and Gemcitabine in Treating Patients With Locally Advanced Pancreatic Cancer
Status:
Terminated
Trial end date:
2013-10-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to
the tumor may kill more tumor cells and cause less damage to normal tissue. Drugs used in
chemotherapy, such as gemcitabine, work in different ways to stop the growth of tumor cells,
either by killing the cells or by stopping them from dividing. Giving intensity-modulated
radiation therapy together with gemcitabine may kill more tumor cells.
PURPOSE: This phase I/II trial is studying the side effects and best dose of
intensity-modulated radiation therapy and to see how well it works when given together with
gemcitabine in treating patients with locally advanced pancreatic cancer.