Intensive Insulin Therapy in Non-diabetic Patients With Acute Myocardial Infarction and Hyperglycaemia

• Status: Completed
• Trial end date: 2007-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Hyperglycemia at admission has been associated with bad prognosis in patients with acute myocardial infarction (AMI). The clinical benefit of intensive treatment with insulin has been evaluated in diabetic patients admitted to intensive care units. The aim of our study was to assess the short-term effects and the safety of strict glycemic control in subjects with AMI and hyperglycemia without a previous history of diabetes.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital Clinic of Barcelona
• Treatments: Insulin; Insulin, Globin Zinc

Criteria

Inclusion Criteria:

1. Confirmed diagnosis of AMI, either with or without ST segment elevation

2. Presence of high blood glucose at admission with no previously known diabetes mellitus (DM)

Exclusion Criteria:

1. Age under 18 years old

2. History of DM

3. Presence of other cardiopathies (dilated cardiomyopathy, valvular or hypertrophic heart disease)

4. Unstable AMI patients (haemodynamic instability or arrhythmic disorders)

5. Platelet aggregation or coagulation disorders

6. Severe conditions with an estimated short (under 1 year) life expectancy

7. Participation in other trials

8. Patient refusal to participate in the study