Intensive Postpartum Antihypertensive Treatment

• Status: Not yet recruiting
• Trial end date: 2026-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

The long-term goal of our work is to evaluate the effect of intensive postpartum blood pressure control on maternal cardiovascular health, risk of chronic hypertension, and reversal of vascular dysfunction generated by hypertensive disorders of pregnancy, thus attenuating the lifelong trajectory of cardiovascular disease risk.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Medical College of Wisconsin
• Treatments: Nifedipine

Criteria

Inclusion Criteria:

• HDP diagnosis (gestational hypertension or preeclampsia) according to ACOG guidelines

• Postpartum day 0-3 and prior to discharge

• Able to communicate in English or in Spanish

• Age 18 - 45

Exclusion Criteria:

• Pre-gestational hypertension

• Pre-gestational diabetes ( type 1 or type 2)

• Intent to transfer postpartum to an outside institution of the participating centers

• Known allergy to nifedipine or other significant contraindication to nifedipine

• Inability or unwillingness to provide informed consent