Intensive Statin Treatment in Acute Ischemic Stroke Patients With INtracranial Atherosclerosis
Status:
Unknown status
Trial end date:
2018-06-01
Target enrollment:
Participant gender:
Summary
Purpose: Intracranial atherosclerosis is a common condition in Korean population consisting
over 25% of ischemic stroke etiology. American Stroke Association and Korean Stroke Society
recommend antiplatelet and statin for the treatment of intracranial atherosclerosis. Besides
lowering blood cholesterol levels statin also stabilize atherosclerotic plaque and eventually
lower the risk of ischemic stroke. However, little evidence resides on the effect of statin
treatment on intracranial atherosclerosis. Recent advance in high-tesla magnetic resonance
imaging enables direct imaging of intracranial atherosclerotic plaque and further assessment
of treatment efficacy of statin in stabilization of intracranial atherosclerotic plaque
became possible.