Interaction Between ABT-335, Rosuvastatin and Warfarin

• Status: Completed
• Trial end date: 2007-07-01
• Target enrollment: 0
• Participant gender: Male

Summary

This is a multiple-dose, double-blind, randomized, single-center, parallel-group study in adult male subjects in general good health.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: AstraZeneca
• Treatments: Fenofibrate; Fenofibric acid; Rosuvastatin Calcium; Warfarin

Criteria

Inclusion Criteria:

• Body mass index (BMI) is 19 to 29, inclusive.

• A condition of general good health, based upon the results of a medical history, physical examination, vital signs, laboratory profile and a 12-lead electrocardiogram (ECG).

• Written informed consent prior to the initiation of screening or study-specific procedures.

Exclusion Criteria:

• Subjects with unstable medical conditions or medical conditions considered inappropriate in a clinical trial.

• Subjects taking concomitant medications.

• Subjects with a recent history of surgery or trauma.

• Subjects with a history of any bleeding disorder.