Overview

Interaction Between Duloxetine and 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy)

Status:
Completed

Trial end date:
2010-05-01

Target enrollment:

Participant gender:

Summary

The purpose of this study is to determinate the effect of a pre-treatment with the combined serotonin (5-HT) and norepinephrine (NE) transport blocker duloxetine on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"). The investigators hypothesize that duloxetine will attenuate the subjective and cardiovascular response to MDMA.

Phase:

Phase 1

Details

Lead Sponsor:

University Hospital, Basel, Switzerland

Treatments:

Duloxetine Hydrochloride
N-Methyl-3,4-methylenedioxyamphetamine