Overview

Interaction Between Fosamprenavir/Ritonavir and a Single-dose Olanzapine (FORZA)

Status:
Completed
Trial end date:
2010-08-01
Target enrollment:
Participant gender:
Summary
The effect of fosamprenavir/ritonavir (steady state) on the pharmacokinetics of a single dose of olanzapine will be studied. In this study, the investigators expect an inducible effect of fosamprenavir/ritonavir on the CYP1A2 and UGT metabolism of olanzapine.
Phase:
Phase 1
Details
Lead Sponsor:
Radboud University
Collaborator:
GlaxoSmithKline
Treatments:
Fosamprenavir
Olanzapine
Ritonavir