Interaction Between NGF and Acute Exercise-induced Ischemia

• Status: Completed
• Trial end date: 2018-06-15
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate pain evoked responses and facilitation of NGF-induced mechanical muscle hyperalgesia over time following an acute exercised-induced ischemic condition in a NGF-sensitized muscle.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Aalborg University
• Treatments: Mitogens

Criteria

Inclusion Criteria:

• Healthy and pain free volunteers

Exclusion Criteria:

• Pregnancy

• Drug addiction defined as the use of cannabis, opioids or other drugs

• Previous neurologic, mental illnesses, or psychiatric diseases.

• Past history of chronic pain in the musculoskeletal system (muscle, joint, cartilage, connective tissue)

• Participation in other pain trials throughout the study period

• Lack of ability to cooperate

• Taking any analgesic 24 hours before the injections

• Performing any strenuous leg exercise through out the study period causing sore muscles