Interaction of Statins and Nondepolarizing Muscle Relaxants

• Status: Unknown status
• Trial end date: 2015-09-01
• Target enrollment: 0
• Participant gender: All

Summary

provide evidence for prevention or reduction muscle pain.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Huang-wei LV
• Treatments: Bromides; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Neuromuscular Nondepolarizing Agents; Rocuronium

Criteria

Inclusion Criteria:

• Patients with American Society of Anesthesiologists physical status I-III

• Patients taking statins for at least 3 months and those who had never used statins were considered to be eligible

Exclusion Criteria:

• Orthopedic

• Spinal surgery

• Surgery involving extensive muscle manipulation

• History of liver and kidney failure

• Neuromuscular disease

• Susceptibility to or family history of malignant hyperthermia

• Extensive denervation of skeletal muscle

• Chronic pain syndromes

• Taking medications that might interact with the effect of rocuronium or serum myoglobin difficult intubation