Interactions of HIV Protease Inhibitors and Methadone in HIV-Infected Patients
Status:
Completed
Trial end date:
2000-09-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to see if it is safe to combine methadone with two HIV protease
inhibitors (PIs), ritonavir (RTV) and saquinavir (SQV), in HIV-infected patients not
currently taking PIs. This study will measure the interactions between methadone and the PIs.
Methadone is used treat addicts and to treat severe pain. In order to find the safest way to
use methadone with PIs, it is important to evaluate how they interact.
Phase:
Phase 1
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Treatments:
HIV Protease Inhibitors Methadone Protease Inhibitors Ritonavir Saquinavir