Interest of the Nefopam and PCA Morphine Combination for Postoperative Analgesia in Patients Undergoing Colon Surgery

• Status: Completed
• Trial end date: 2012-01-01
• Target enrollment: 0
• Participant gender: All

Summary

This study analyses interest of iv nefopam in combination with paracetamol after major abdominal surgery because the effect of morphine-sparing is discussed when combined these agents.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Centre Hospitalier Universitaire de Nīmes
• Treatments: Morphine; Nefopam

Criteria

Inclusion Criteria:

• Adult patient with a score ASA between I and III

• Patient scheduled for elective major abdominal surgery (by laparotomy) for cancer or diverticulosis

• Patient that signed the consent form

Exclusion Criteria:

• - Patient treated in emergency situation

• Patient with chronic inflammatory bowel disease (Crohn's disease, ulcerative colitis)

• Patient that needs a surgery for restoration of continuity

• Patient pregnant, breastfeeding, or during periods of genital activity using no contraception.

• Patient with contraindications to nefopam, morphine, or paracetamol

• Patient with chronic obstructive pulmonary disease, renal or severe hepatic impairment

• Patient under analgesics treatment

• Patient who participated in a clinical study in the previous 6 months.