Intermittent Bolus vs Continuous Infusion Via ESP Catheters RCT
Status:
Recruiting
Trial end date:
2023-12-31
Target enrollment:
Participant gender:
Summary
The purpose of this prospective randomized controlled trial is to compare the effectiveness
of two different delivery methods for postoperative pain management following cardiac surgery
requiring median sternotomy: intermittent programmed LA bolus versus continuous LA infusion
through ESP catheters. Effectiveness of analgesia will be assessed based on the subjects' NRS
pain scores and opioid consumption. The primary outcome measure will be the patients' opioid
consumption over the course of the 72 hours following surgery. Secondary outcomes measures
that will be evaluated include NRS pain scores, intensive care unit (ICU) length of stay, and
time to first dose of antiemetic in the postoperative period. It is hypothesized that the use
of intermittent programmed LA boluses will provide better analgesia compared to continuous LA
infusion through ESP catheters. The findings of this study will provide guidance regarding
the optimal method of delivery for postoperative pain management in patients following
cardiac surgery.