Intermittent Preventive Treatment of Malaria in School-age Children to Decrease Community Transmission
Status:
NOT_YET_RECRUITING
Trial end date:
2029-05-31
Target enrollment:
Participant gender:
Summary
The CRITICal study aims to estimate the effectiveness of intermittent preventive treatment in school children (IPTsc) with dihydroartemisinin-piperaquine (DP) for reducing community level malaria burden. Given that school-aged children are the primary drivers of transmission, the study hypothesis is that IPTsc will reduce this infectious reservoir and thus the burden of malaria in persons of all ages in surrounding communities.
Phase:
PHASE4
Details
Lead Sponsor:
University of California, San Francisco
Collaborators:
Infectious Diseases Research Collaboration, Uganda Ministry of Health, Uganda National Institute of Allergy and Infectious Diseases (NIAID)