International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma
Status:
Recruiting
Trial end date:
2024-04-01
Target enrollment:
Participant gender:
Summary
The study PNET 5 MB has been designed for children with medulloblastoma of standard risk
(according to the risk-group definitions which have been used so far; e.g. in PNET 4). With
the advent of biological parameters for stratification into clinical medulloblastoma trials,
the ß-catenin status will be the only criterion according to which study patients will be
assigned to either treatment arm PNET 5 MB - LR or to PNET 5 MB - SR, respectively. The
initial diagnostic assessments (imaging, staging, histology, and tumor biology) required for
study entry are the same for both treatment arms.