Overview

International Trial of Selumetinib in Combination With Dexamethasone for the Treatment of Acute Lymphoblastic Leukaemia

Status:
Recruiting
Trial end date:
2022-05-01
Target enrollment:
Participant gender:
Summary
This trial is to investigate the combination of selumetinib and dexamethasone in the treatment of acute lymphoblastic leukaemia (ALL) in both adults and children. Phase I is to find the most suitable dose of selumetinib to safely give with dexamethasone. Phase II will use this dose to find out how well the combination works.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
University of Birmingham
Collaborators:
AstraZeneca
Cancer Research UK
Treatments:
BB 1101
Dexamethasone
Dexamethasone acetate