Interscalene Nerve Blocks With Ropivacaine Alone, With Dexamethasone, Plus Systemic Dexamethasone

• Status: Terminated
• Trial end date: 2009-03-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will test the hypothesis that ropivacaine in combination with either systemic or local steroid provides comparably longer-lasting analgesia tha ropivacaine alone.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Cleveland Clinic
• Treatments: BB 1101; Bupivacaine; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Ropivacaine

Criteria

Inclusion Criteria:

• Patients undergoing open shoulder procedures such as rotator cuff repair, capsular shift, subacromial decompression

• Age between 18 and 70 years

Exclusion Criteria:

• Contradictions for interscalene block

• Coagulopathy

• Infection at the needle insertion site

• Moderate to severe chronic obstructive pulmonary disease (COPD)

• Contralateral pneumothorax of diaphragmatic paralysis

• Pregnancy

• Preexisting neuropathy involving the surgical limb

• Systemic glucocorticoid treatment within the last six months of surgery

• Routine opioid use