Interventions for Residual Dizziness After Successful Repositioning Maneuvers in Patients With BPPV

• Status: Unknown status
• Trial end date: 2020-07-31
• Target enrollment: 0
• Participant gender: All

Summary

To investigate the effect of vestibular rehabilitation, with or without medication, on resolving residual dizziness after successful repositioning maneuvers in patients with benign paroxysmal positional.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Eye & ENT Hospital of Fudan University
• Treatments: Betahistine

Criteria

Inclusion Criteria:

1. Diagnosed as unilateral BPPV (unilateral posterior semicircular canal BPPV or horizontal semicircular canal BPPV) according to the clinical practice guideline issued by American Academy of Otolaryngology and head and neck surgery (AAO-HNSF) in 2017;

2. Aged 18~80 years;

3. Reporting residual symptoms after successful repositioning maneuvers;

Exclusion Criteria:

1. Anterior semicircular canal BPPV or multicanal BPPV;

2. Recurrent BPPV;

3. Subjects with coexisting vestibular disorders, including Meniere disease, vestibular neuritis, labyrinthitis, and peripheral vestibular loss;

4. Subjects with severe cervical spine disease;

5. Subjects with severe cardiovascular diseases ;

6. Subjects with known cerebral vascular disease like carotid stenosis;

7. Cognitive impairment;

8. Suspect of significant depression or anxiety as defined as a score of ≥ 8 for each respective scale of Hospital anxiety and depression scale;

9. Pregnant/ lactating or planning to become pregnant during the study period;

10. Had taken vestibulosupressant, antihistamines, and/ or ototoxic medications in the past 3 months;