Overview

Intra Amniotic Injection of DIGOXIN for Feticide in Second Trimester Termination of Pregnancy

Status:
Unknown status
Trial end date:
2014-12-01
Target enrollment:
0
Participant gender:
Female
Summary
In second trimester abortion above 22 weeks the investigators usually inject intra-cardiac Kcl for feticide. Digoxin intra-amniotic injection has been described in the literature in doses of 1-1.5 mg. with a success rate of about 80%, and up to 24 weeks. Our aim in this study is to investigate the safety and success rate of 1.5-2 mg. digoxin, intra-amniotic up to 30 weeks pregnancy .
Phase:
Phase 3
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Meir Medical Center
Treatments:
Digoxin
Criteria
Inclusion Criteria:

- healthy women with no medical, cardiac, hypertension, liver or renal problems -
pregnant in their 20-30 week gestation,

- that need to have abortion due to fetal anomalies or any other reason

- need to have feticide prior to the procedure

Exclusion Criteria:

- any patient with medical problem that may be a contra-indication to Digoxin

- cardiac problems,

- prior cardiac surgery,

- liver or kidney disease,

- hyper tension etc.