Intra-arterial Melphalan in Treating Younger Patients With Unilateral Retinoblastoma
Status:
Active, not recruiting
Trial end date:
2021-09-30
Target enrollment:
Participant gender:
Summary
This pilot clinical trial studies whether unilateral group D retinoblastoma, or
retinoblastoma affecting one eye that has spread to the inner jelly like part of the eye, can
be treated with a new technique for delivering chemotherapy directly into the blood vessel
that supplies the affected eye. This new technique is called intra-arterial injection. Giving
melphalan via intra-arterial injection may make it less likely that children will need
surgery to remove the eye and may reduce the amount of treatment side effects.