Overview

Intra-arterial Neuroprotective Strategy for Ischemic STroke Patients With Endovascular Therapy (INSIST-ET)

Status:
Recruiting
Trial end date:
2021-12-01
Target enrollment:
0
Participant gender:
All
Summary
To explore the safety and feasibility of intra-arterial neuroprotective strategy in acute ischemic stroke patients who received recanalization operation.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Hui-Sheng Chen
Treatments:
Neuroprotective Agents
Criteria
Inclusion Criteria:

1. Age ≥18 years;

2. Acute ischemic stroke patients who is eligible for endovascular treatment;

3. Signed informed consent.

Exclusion Criteria:

1. Modified Rankin Score >2 caused by a history of prior stroke;

2. Coagulation disorders, systematic hemorrhagic tendency, thrombocytopenia (<80000/mm3);

3. Severe hepatic or renal dysfunction, increase in ALT or AST (more than 2 times of
upper limit of normal value), increase in serum creatinine (more than 1.5 times of
upper limit of normal value) or requiring dialysis;

4. Severe hypertension (systolic blood pressure over 200mmHg or diastolic blood pressure
over 110 mmHg);

5. Unsuitable for this clinical studies assessed by researcher.