Intra-arterial Tenecteplase During First Thrombectomy Attempt for Acute Stroke (BRETIS-TNK II)
Status:
Not yet recruiting
Trial end date:
2025-02-15
Target enrollment:
Participant gender:
Summary
A recent pilot study suggests intra-arterial tenecteplase (TNK) during the first pass of
endovascular treatment (EVT) seems safe, may increase first-pass reperfusion and good outcome
in acute ischemic stroke (AIS) patients with large vessel occlusion (LVO).
The study aimed to determine the efficacy and safety of intra-arterial TNK administration
during EVT in AIS-LVO patients.
Phase:
Phase 3
Details
Lead Sponsor:
General Hospital of Shenyang Military Region
Collaborator:
Cerebrovascular Disease Collaboration & Innovation Alliance of Liaoning