Intra-articular Administration of 3.0g Tranexamic Acid Has no Effect on Reducing Intra-articular Hemarthrosis and Postoperative Pain After Primary Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial

• Status: Unknown status
• Trial end date: 2019-08-30
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study was to investigate whether intraarticular administration of tranexamic acid could reduce hemarthrosis and postoperative pain in patients following anterior cruciate ligament reconstruction. The hypothesis of the study was that patients treated with intraarticular tranexamic acid would have significantly less postoperative hemarthrosis and less pain in the early phase of the rehabilitation process compared with those without intraarticular tranexamic acid .

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Korea University Guro Hospital
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• primary single bundle anterior cruciate ligament reconstruction using a hamstring autograft with or without meniscus surgeries

Exclusion Criteria:

• use of other grafts (allograft, bone patellar tendon bone autograft)

• revision anterior cruciate ligament reconstruction,

• concomitant knee cartilage or collateral ligament surgeries

• history of knee surgery on affected knee

• concomitant fracture

• significnat preoperative pain (Visual analoge score >5)

• coagulation or bleeding disorders

• preoperative anticoagulation treatment