Intra-articular Versus Intravenous Dexmedetomidine in Arthroscopic Knee Surgeries Under Local Anesthesia
Status:
Completed
Trial end date:
2016-05-30
Target enrollment:
Participant gender:
Summary
The present study will be carried to evaluate the efficacy of intra-articular 0.5 bupivacaine
with intra-articular or intravenous alpha-2agonist; Dexmedetomidine; for intraoperative
anesthesia and postoperative analgesia after arthroscopic knee surgery.
Arthroscopic knee surgery is one of the most common minimally invasive orthopedic procedures
in recent practice which is frequently performed as a day surgery procedures. It can be done
under general, regional or local anesthesia (LA) with or without sedation. It is associated
with varying amount of postoperative pain. Postoperative pain negatively influences patient's
early ambulation, rehabilitation and psychology which consecutively prolonged the hospital
stay.
Intra-articular administration of local anesthetic for knee arthroscopy is a well-documented
procedure that offers many advantages over other anesthesia types. Many anesthesiologists are
still trying to improve the technique of local anesthetic administration through using many
combinations with LA solutions in order to administer safe anesthesia to those patients and
to obtain a pain-free knee with good operating conditions.
Dexmedetomidine is a highly selective α2 adrenergic agonist. It has analgesic, sedative,
anxiolytic, hypnotic, sympatholytic, antihypertensive properties with anesthetic sparing
effects. It becomes an attractive alternative to the current opioids because it does not have
a respiratory depressant or addictive effect.