Intradialytic Parenteral Nutrition in Hemodialysis Patients

• Status: Completed
• Trial end date: 2010-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Malnutrition is a major cause of death in chronic hemodialysis patients. Primary treatment of malnutrition in these patients is dietetic counseling, additional enteral nutrition and occasionally drug therapy.

In cases where primary treatment of malnutrition is not effective, intradialytic parenteral nutrition (IDPN)during dialysis therapy may be administered. Using IDPN aminoacids, carbohydrates and fatty acids as well as vitamins and trace elements can be given to the patients.

Effectiveness of IDPN has to be verified.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Fresenius Kabi
• Collaborator: Institute for Clinical Research

Criteria

Inclusion Criteria:

• hemodialysis therapy more than 6 months

• three times per week hemodialysis

• albumin < 35 g/l

• prealbumin < 250 mg/l

• phase angle < 4,5°

• SGA score grade B or C

• informed consent

Exclusion Criteria:

• inadequate dialysis (Kt/V < 1,2)

• chemotherapy or radiotherapy

• cardiac pacemaker

• acute bacterial infection

• acute immunological disease

• cancer disease

• severe hepatic insufficiency

• interferon therapy

• HIV disease

• severe diabetes mellitus