Intraligamentary Injections and Post-endodontic Pain

• Status: Recruiting
• Trial end date: 2024-03-03
• Target enrollment: 0
• Participant gender: All

Summary

This study will aim to evaluate postoperative pain after intraligamentary injections of dexamethasone (4mg/ml), diclofenac sodium (25mg/ml), 0.5% bupivacaine and 2% lidocaine given to the patients with symptomatic irreversible pulpitis after completion of the first appointment. Objectives: 1. To evaluate postoperative pain in patients receiving intraligamentary injections of either dexamethasone (4mg/ml), diclofenac sodium (25mg/ml), 0.5% bupivacaine or 2% lidocaine. 2. To compare the postoperative pain in different groups.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Jamia Millia Islamia
• Treatments: Bupivacaine; Dexamethasone; Diclofenac

Criteria

Inclusion Criteria:

• Symptomatic carious exposed mandibular first or second molars.

• Positive and prolonged response to thermal sensitivity tests and electric pulp tests.

• Vital coronal pulp on access cavity preparation.

• American Society of Anesthesiologists class I or II medical history.

• Ability to understand the use of pain scales.

Exclusion Criteria:

• Active pain in more than 1 tooth

• Teeth with fused roots.

• Radiographic evidence of an extra root.

• Large restorations with overhanging margins.

• Full crowns or deep periodontal pockets.

• Known allergy or contraindications to any content of the local anesthetic solution or NSAIDs

• History of known or suspected drug abuse.

• Taking any drugs which could affect the pain perception, e.g, opioids, antidepressants, anticonvulsants, muscle relaxants, anxiolytics, sedatives, NSAIDs.

• Pregnant or breastfeeding patients.

• Patients with asthma, gastric ulcers, and bleeding disorders.