Intramyocardial Haemorrhage in Patients With Primary STEMI

• Status: Completed
• Trial end date: 2019-03-20
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to assess the frequency and intensity of intramyocardial haemorrhage in patients with primary STEMI and different reperfusion strategies.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences
• Treatments: Streptokinase; Tenecteplase

Criteria

Inclusion Criteria:

• Age ≥ 18 years at time of randomization (18 years and older);

• Acute myocardial infarction;

• Reperfusion of the infarct-related coronary artery in terms within 12 h of symptom onset;

• Written the informed consent to participate in research;

Exclusion Criteria:

• Inability to obtain informed consent;

• Patients previously undergone endovascular / surgical revascularization of coronary artery;

• Severe comorbidity;

• History of myocardial infarction;

• History of intracranial haemorrhage;

• Pulmonary edema, cardiogenic shock;

• Creatinine clearance <30 mL/min or dialysis;

• Unable to undergo or contra-indications for MRI;

• Allergy for contrast agent;

• Indication or use of oral anticoagulant therapy;

• Major bleedind;

• Atrio-ventricular block II and III degree;

• Active gastroduodenal ulcer;

• Aortic dissection;

• Acute psychotic disorders