Intranasal Ketamine and Midazolam Mixture for Procedural Sedation in Children With Mental Disabilities:

• Status: Unknown status
• Trial end date: 2019-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Ketamine and Midazolam are well known sedative drugs that can be given through different routes such as intravenous, intramuscular, oral, rectal and intranasal route. Anesthetic staff usually prefer intravenous route but sometimes inserting venous access is difficult in uncooperative mentally disabled children. Intranasal ketamine+Midazolam can be a needless effective alternative in these vulnerable patients

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Ketamine; Midazolam

Criteria

Inclusion Criteria:

• Inclusion criteria of the patients were:

• Mentally affected children (autism,down syndrome and cerebral palsy)

• children who are scheduled for Short procedures (30 minutes or less) under sedation

Exclusion Criteria:

• parents refusal.

• child cooperation and acceptance of venipuncture or cannula in situ.

• children with known allergy to ketamine or midazolam.

• liver or renal organ dysfunction.

• suspected difficult cannulation.

• congenital heart disease.

• active pulmonary infection or asthma.

• increased intracranial tension or intraocular pressure.

• severe trauma0

• significant nasal discharge or obstruction.