Intraoperative Chemotherapy Against Hepatocellular Carcinoma Recurrence
Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
Participant gender:
Summary
Hepatectomy is still the most important treatment for HCC.High recurrence rate mostly
influence it's prognosis, especially for the patient with tumor >5cm, multiple tumor and who
cannot accept R0 resection.Our retrospective study showed sustained released 5-FU implanted
into the liver incisal margin after tumor was resected could reduce the recurrence rate of
HCC after liver resection.According to this, we proceed this RCT to prospectively observe the
effect of sustained released 5-FU,and we also want to know whether combined with sustained
released cisplatin will get better effect in preventing the tumor recurrence,especially in
short time after liver resection.