Intraoperative Contrast-Enhanced Ultrasound Evaluation of Blood Flow at the Time of Surgical Hip Reduction for DDH

• Status: Recruiting
• Trial end date: 2027-04-01
• Target enrollment: 0
• Participant gender: All

Summary

This study evaluates the feasibility and utility of contrast-enhanced ultrasound to provide real-time assessment of blood flow to the femoral head in infants undergoing surgical reduction for developmental dysplasia of the hip.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Children's Hospital of Philadelphia
• Collaborator: Bracco Diagnostics, Inc

Criteria

Inclusion Criteria:

• Males or females between 4 months and up to and including 24 months of age at the time of surgery.

• Diagnosed with developmental dysplasia of the hip

• Failed conservative treatment and will undergo closed or open reduction and spica casting

• Informed consent

Exclusion Criteria:

• > 24 months of age o at the time of surgery

• Subjects with DDH who are successfully treated with conservative measures and do not require surgery

• Known heart or pulmonary condition

• History of hypersensitivity reactions to sulfur hexafluoride lipid microsphere components