Intraoperative IV Iron on Postoperative Red Blood Cell Recovery

• Status: Not yet recruiting
• Trial end date: 2021-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of the present study is to determine the impact of intraoperative IV-iron supplementation on postoperative recovery of RBC mass by retrospectively analyzing and comparing the changes of postoperative hematocrit values after the surgery in patients underwent elective uni-limb total knee arthroplasty surgery with or without IV-iron supplementation during surgery

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Konkuk University Medical Center
• Treatments: Ferric Compounds

Criteria

Inclusion criteria

• Patients with osteoarthritis in knee joint undergoing elective uni-limb total knee arthroplasty surgery

• Patients provided a written informed consent.

• Patients with s-ferritin < 300 mg/dl (male) or 200 mg/dl (female)

• Patients with preoperative serum hemoglobin concentration >10 g/dL

Exclusion criteria

• Patients with history of anaphylaxis, iron overload, active infection.

• Patients received or receiving intraoperative and preoperative blood salvaged, allogenic blood transfusion, recombinant human erythropoietin, or undergoing acute normovolemic hemodilution.