Intraperitoneal Dexmedetomidine Versus Ketamine With Bupivacaine For Postoperative Analgesia
Status:
Recruiting
Trial end date:
2021-10-20
Target enrollment:
Participant gender:
Summary
Post-laparoscopic sleeve pain management is essential for early mobilization of the patient
and so on decrease post-operative complication. The use of opioids is associated with adverse
effects such as nausea, pruritus, sedation, and occasionally respiratory depression.
Previous studies stated that intraperitoneal instillation of bupivacaine alone has been used
to reduce acute postoperative abdominal and shoulder pain allow early mobilization and
decrease postoperative opioid requirements and its complications.
In this study the investigators will compare between intraperitoneal instillation of
dexmedetomidine with bupivacaine versus ketamine with bupivacaine in patients undergoing
laparoscopic sleeve gastrectomy under general anesthesia regarding to postoperative pain
relief to reduce morbidity and mortality.