Intraperitoneal Instillation of Levobupivacaine With Morphine Versus Levobupivacaine With Magnesium Sulfate for Postoperative Analgesia

• Status: Completed
• Trial end date: 2021-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a prospective randomized study that included 60 patients and was divided into two equal groups of patients who were scheduled for LC, Ages 18 and 60 years, both sexes, ASA I-II and BMI 19 - 39. Group A received 30 ml levobupivacaine (0.25%) plus 3 mg morphine intraperitoneal at the site of surgery in the bed of the gallbladder via the navel port with the patient in a Trendelenburg position, Group B received 30 ml levobupivacaine (0.25%) plus 50 mg/kg magnesium sulfate in the same pattern as in the A group.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sohag University
• Treatments: Levobupivacaine; Morphine

Criteria

Inclusion Criteria:

• Patients who were scheduled for L.C,

• Ages 18 and 60 years

• ASA I-II and

• BMI 19 - 39

Exclusion Criteria:

• Patients with hepatic or renal dysfunction

• use of opioids 24 hrs prior to the study

• treatment with steroids prior to surgery

• drug or alcohol abuse, allergy to any of the study drugs

• chronic pain syndrome as a result of neurological disease